Purported Uses of Sangre de GradoJason
Taspine is an alkaloid which acts as a potent acetylcholinesterase inhibitor. Taspine has also been found to be a dual topoisomerase inhibitor effective in cells overexpressing drug efflux transporters and induces wide-spread apoptosis in multicellular spheroids.
Taspine promotes early phases of wound healing in a dose-dependent manner with no substantial modification due to its mechanism of action related to its chemotactic properties on fibroblasts.
Taspine has also shown anti-inflammatory potential.
Dimethylcedrusine, another biologically active substance in Sangre de Grado, was shown to inhibit thymidine incorporation, while protecting cells against degradation in a starvation medium.
Sangre de grado exerts anti-viral effects against influenza viruses, parainfluenza viruses, herpes simplex viruses types I and II, hepatitis A virus and hepatitis B virus.
Sangre de grado may also present a complementary and alternative medicine approach for the treatment of fluid loss in watery diarrhea.
Sangre de grado has also been found to induce apoptosis in human gastrointestinal cancer cells.