THE JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE Volume 9, Number 6, 2003, pp. 813B815 8 Mary Ann Liebert, Inc. Biocultural Diversity, Phytomedicines, and Tropical Rainforests: The Holistic Link from Practitioner to Cultures of the Tropical Rainforest STEVEN R. KING, Ph.D. PHOTOESSAY 813 Shaman Pharmaceuticals, South San Francisco, CA. Left: An illustration of local people collecting […]
Scientific Studies
Inhibition of Neurogenic In¯ammation by the Amazonian Herbal Medicine Sangre de Grado (PDF Download)
To read this article please download the pdf: Herbal Medicine Sangre De Grado
A novel extract SB-300 from the stem bark latex of Croton lechleri inhibits CFTR-mediated chloride secretion in human colonic epithelial cells.
Fischer H1, Machen TE, Widdicombe JH, Carlson TJ, King SR, Chow JW, Illek B. An oligomeric proanthocyanidin (SP-303) extracted from the bark latex of the tree Croton lechleri (family Euphorbiaceae) is a potent inhibitor of cholera toxin-induced fluid accumulation and chloride secretion. The manufacturing process for SP-303 was optimized and simplified to produce an […]
Crofelemer, an Antisecretory Antidiarrheal Proanthocyanidin Oligomer Extracted from Croton lechleri, Targets Two Distinct Intestinal Chloride Channels
Mol Pharmcol. Crofelemer, a purified proanthocyanidin oligomer extracted from the bark latex of Croton lechleri, is in clinical trials for secretory diarrheas of various etiologies. We investigated the antisecretory mechanism of crofelemer by determining its effect on the major apical membrane transport and signaling processes involved in intestinal fluid transport. Using cell lines and measurement […]
Mutagenic and antioxidant activities of Croton lechleri sap in biological systems.
The sap of Croton lechleri Muell.-Arg (Euphorbiaceae), called Dragon’s blood, is used in folk medicine as a cicatrizant, anti-inflammatory and to treat cancer. In this research, the antioxidant activity of Croton lechleri sap was evaluated against the yeast Saccharomyces cerevisiae and against maize plantlets treated with the oxidative agents apomorphine and hydrogen peroxide. The mutagenic […]
Blood of dragon, powerful natural healing
The Blood of Drago is a latex extracted from the bark of an Amazonian tree. It has been traditionally used by natives to treat problems of diarrhea, gastritis and as a natural scar. It has Natural Healing Properties Translated from original Text Drago or Grade Blood is the latex extracted from the bark […]
Modern Research about Sangre De Grado
Introduction Croton lechleri is a medium-sized tree (10-20 meters or 30-60 feet) native to the Amazonian region of the South American countries of Bolivia, Brazil, Colombia, Ecuador, and Peru. It most commonly grows in the northwest lowland Amazonian forest area in disturbed soil and along rivers and streams.1-4 Despite its height, the tree has a […]
Antioxidant Activity of Sangre de Grado
Another important health benefit to Sangre de Grado is its potential as a powerful antioxidant herb. An article published in the Nutrition Journal in 2010 entitled The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide, by Monica H Carlsen, Bente L Halvorsen, Kari Holte, Siv K Bøhn, Steinar […]
Purported Uses of Sangre de Grado
Taspine is an alkaloid which acts as a potent acetylcholinesterase inhibitor. Taspine has also been found to be a dual topoisomerase inhibitor effective in cells overexpressing drug efflux transporters and induces wide-spread apoptosis in multicellular spheroids. Taspine promotes early phases of wound healing in a dose-dependent manner with no substantial modification due to its mechanism […]
Dragon’s Blood: Great for Skin
By the side of a rutted, muddy road up the Rio Aguaytia in the Peruvian Amazon, my friends and I stopped to admire a stand of Croton lechleri – Dragon’s blood trees. The tall trees bore a mottled-white and gray bark, and a couple of the trees also featured diagonal slashes. They had been previously […]